Dasatinib |
Inhibits YES1 |
[21] |
Verteporfin, flufenamic acid |
Disrupt YAP-TEAD interaction |
[133,134] |
YAP-like and VGLL4-like peptides |
Disrupt YAP-TEAD interaction |
[135,136,137] |
XAV939, Inhibitor of WNT response 1 (IWR-1), G007-LK |
Inhibit tankyrases to stabilize AMOTs |
[138,139,140] |
093G9 |
Monoclonal antibody against CYR61 |
[141] |
FG-3019 |
Monoclonal antibody against CTGF |
[142] |
Foretinib, sunitinib |
Small molecule inhibitors of AXL |
[143] |
Navitoclax (ABT-263) |
Small molecule inhibitor of BCL-XL |
[144] |
Digitoxin |
May inhibit WBP2-YAP interaction |
[145,146] |
9E1 |
Small molecule inhibitor of MST1 |
[147] |
BrP-LPA |
Inhibits synthesis of LPA |
[148] |
ABC294640 |
Small molecule inhibitor of SPHK2 |
[149] |
Statins |
Inhibit mevalonate pathway |
[150,151] |
Antagomir against miR-135b |
Derepression of LATS2, MOB1B
|
[152] |
Antagomir against miR-130b |
Derepression of MST1, SAV1
|
[153] |
MiR-302 mimic |
Repression of MST1, LATS2, MOB1B
|
[154] |