Table 2. Quantitative comparison of class total lipid profiles in placenta.
Lipid Class (μmol/g tissue) | Control (n = 68) | PET (n = 23) | IUGR (n = 10) | P |
---|---|---|---|---|
TAG* | 0.20 (0.11)1 | 0.27 (0.12)2 | 0.15 (0.05)1 | 0.001 |
CE* | 0.31 (0.10)1 | 0.42 (0.16)2 | 0.28 (0.10)1 | 0.004 |
Cholesterol | 2.9 (0.5)1 | 3.4 (0.8)2 | 3.2 (0.7)1,2 | 0.006 |
PC | 3.2 (0.8)1 | 3.7 (1.1)2 | 3.5 (1.0)1,2 | 0.025 |
PE | 0.93 (0.25) | 1.07 (0.38) | 1.01 (0.31) | 0.169 |
PS | 0.36 (0.09) | 0.40 (0.10) | 0.40 (0.13) | 0.127 |
SM | 0.71 (0.18) | 0.82 (0.26) | 0.88 (0.22) | 0.014 |
Total PL | 5.2 (1.2)1 | 6.0 (1.7)2 | 5.7 (1.6)1,2 | 0.029 |
Cer | 0.06 (0.02) | 0.06 (0.03) | 0.06 (0.02) | 0.605 |
Total Lipid | 8.6 (1.7)1 | 10.1 (2.4)2 | 9.4 (2.4) 1,2 | 0.006 |
CE, cholesteryl ester; Cer, ceramides; IUGR, intrauterine growth restriction; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PET, preeclampsia; PL, phospholipid; PS, phosphatidylserine; SM, sphingomyelin; TAG, triacylglycerol.
Values are mean (SD).
ANOVA was used to test for differences among groups (*on log transformed data). Different superscript numbers indicate differences between individual groups using post hoc Tukey test. Significance level P<0.05.