Table 4. Results of the TKI treatment according to the EGFR mutations.
Group1 MT in PT & LN | Group2 MT in PT & WT in LN | Group3 majMT in PT & LN | Group4 majMT in PT & WT in LN | Group5 WT in PT & LN | |
---|---|---|---|---|---|
PR+SD | 17/23(73.9%) | 2/3(66.7%) | 16/19(84.2%) | 2/3(66.7%) | 3/16 (18.8%) |
PD | 6/23(26.1%) | 1/3(33.3%) | 3/19(15.8%) | 1/3(33.3%) | 13/16(81.2%) |
TKI; tyrosine kinase inhibitor, MT; any mutation, majMT; major mutation, WT; wild type, PR; partial response, SD; stable disease, PD; progressive disease
Group 1 vs. Group 2; p = 1.00, Group3 vs. Group4; p = 0.47, Group 1+2 vs. Group5, p = 0.001, Group 3+4 vs. Group5, p = 0.0002