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. 2016 Sep 29;11(9):e0163879. doi: 10.1371/journal.pone.0163879

Table 6. Hematological data of monkeys fed on diets containing GM rice or non-GM rice.

Time Group RBC HGB HCT MCV MCH MCHC PLT MPV %Retic #Retic
(1012/L) (g/L) (%) (fL) (pg) (g/L) (109/L) (fL) (%) (1012/L)
Pre-dose Non-GM rice 5.67±0.66 135.13±20.08 47.28±6.29 83.39±5.13 23.80±1.65 285.75±14.38 406.00±76.87 9.46±1.09 1.60±0.66 87.63±30.87
Positive control 6.11±0.69 146.50±11.68 49.70±4.45 81.55±4.05 24.05±1.34 295.25±7.63 370.50±16.05 9.60±1.78 1.40±0.67 81.25±33.33
17.5% GM rice 5.82±0.64 138.00±18.80 47.86±6.86 82.09±5.49 23.71±1.68 288.63±8.11 398.88±90.18 9.24±0.82 1.54±0.41 88.50±18.34
70% GM rice 5.98±0.77 141.58±18.14 49.35±5.42 82.78±5.02 23.68±1.24 286.08±8.94 372.83±101.11 9.33±1.21 1.33±0.33 80.00±19.92
Treatment Month 1 Non-GM rice 5.18±0.35 125.00±10.16 43.20±3.90 83.39±5.30 24.08±1.32 289.38±15.81 419.63±41.87 9.20±0.85 1.34±0.3 68.75±15.39
Positive control 5.35±0.35 127.50±5.00 42.85±2.23 80.25±3.69 23.88±0.88 297.75±6.80 399.75±56.15 9.05±1.52 1.35±0.51 71.25±26.36
17.5% GM rice 5.34±0.42 128.25±7.94 43.56±2.85 81.69±4.39 24.10±1.56 294.75±9.22 375.13±63.77 9.14±0.54 1.25±0.43 66.50±20.13
70% GM rice 5.38±0.43 126.25±9.28 43.94±3.78 81.80±5.37 23.48±1.09 287.58±10.93 379.42±77.83 9.04±1.36 1.09±0.29 57.58±13.80
Treatment Month 3 Non-GM rice 5.19±0.44 124.13±8.31 42.60±2.85 82.28±4.61 23.98±1.18 291.88±13.41 445.13±93.09 9.11±0.77 1.64±0.80 81.75±34.62
Positive control 5.55±0.38 129.75±5.32 43.23±1.97 78.05±3.78 23.45±0.61 300.25±7.50 405.75±46.64 9.10±1.44 1.28±0.59 69.50±28.45
17.5% GM rice 5.32±0.38 124.25±11.06 42.15±3.14 79.33±4.76 23.38±1.68 294.75±8.84 425.50±78.18 9.01±0.59 1.23±0.27 58.25±22.79
70% GM rice 5.33±0.50 124.00±10.30 42.89±3.69 80.75±4.83 23.32±1.33 289.08±7.67 397.33±84.31 9.14±1.20 1.38±0.52 71.67±24.51
Treatment Month 6 Non-GM rice 5.07±0.49 129.50±8.11 43.84±3.30 86.66±4.45 25.63±1.17 295.88±9.72 409.38±45.24 9.40±0.71 1.34±0.46 66.85±18.84
Positive control 4.89±0.53 122.25±6.40 39.53±3.84 81.15±4.59 25.15±1.48 310.25±15.65 412.00±13.22 9.20±0.88 0.10±0.00** 4.38±1.71**
17.5% GM rice 5.33±0.56 133.50±12.95 44.86±4.39 84.31±5.48 25.13±1.69 297.88±11.05 424.50±95.20 9.10±0.85 1.09±0.40 57.58±18.92
70% GM rice 5.40±0.63 132.08±12.49 45.41±3.69 84.53±5.23 24.57±1.34 290/83±7.58 364.67±80.52 9.45±1.09 1.12±0.43 58.53±19.64
Recovery Non-GM rice 4.55 123.00 39.90 87.65 26.95 307.50 343.00 9.45 1.10 49.50
Positive control / / / / / / / / / /
17.5% GM rice 4.89±0.45 129.75±8.18 40.98±2.03 84.15±6.13 26.65±2.55 316.50±8.89 434.00±87.96 8.68±0.62 1.25±0.49 59.53±18.82
70% GM rice 5.48±0.87 137.50±11.09 44.73±3.36 82.50±7.18 25.38±2.47 307.50±7.42 327.00±81.18 8.65±1.01 1.03±0.56 52.73±23.10

Note: Data are presented as the mean±SD. During the quarantine period and the study period, there were 8, 4, 8 and 12 animals in the non-GM rice, positive control, 17.5% GM rice and 70% GM rice groups, respectively, whereas there were 2, 0, 4 and 4 animals in the four respective group during the recovery period.

*: Significantly different from the non-GM rice group at p<0.05.

**: Significantly different from the non-GM rice group at p<0.01.