Table 6. Hematological data of monkeys fed on diets containing GM rice or non-GM rice.
Time | Group | RBC | HGB | HCT | MCV | MCH | MCHC | PLT | MPV | %Retic | #Retic |
---|---|---|---|---|---|---|---|---|---|---|---|
(1012/L) | (g/L) | (%) | (fL) | (pg) | (g/L) | (109/L) | (fL) | (%) | (1012/L) | ||
Pre-dose | Non-GM rice | 5.67±0.66 | 135.13±20.08 | 47.28±6.29 | 83.39±5.13 | 23.80±1.65 | 285.75±14.38 | 406.00±76.87 | 9.46±1.09 | 1.60±0.66 | 87.63±30.87 |
Positive control | 6.11±0.69 | 146.50±11.68 | 49.70±4.45 | 81.55±4.05 | 24.05±1.34 | 295.25±7.63 | 370.50±16.05 | 9.60±1.78 | 1.40±0.67 | 81.25±33.33 | |
17.5% GM rice | 5.82±0.64 | 138.00±18.80 | 47.86±6.86 | 82.09±5.49 | 23.71±1.68 | 288.63±8.11 | 398.88±90.18 | 9.24±0.82 | 1.54±0.41 | 88.50±18.34 | |
70% GM rice | 5.98±0.77 | 141.58±18.14 | 49.35±5.42 | 82.78±5.02 | 23.68±1.24 | 286.08±8.94 | 372.83±101.11 | 9.33±1.21 | 1.33±0.33 | 80.00±19.92 | |
Treatment Month 1 | Non-GM rice | 5.18±0.35 | 125.00±10.16 | 43.20±3.90 | 83.39±5.30 | 24.08±1.32 | 289.38±15.81 | 419.63±41.87 | 9.20±0.85 | 1.34±0.3 | 68.75±15.39 |
Positive control | 5.35±0.35 | 127.50±5.00 | 42.85±2.23 | 80.25±3.69 | 23.88±0.88 | 297.75±6.80 | 399.75±56.15 | 9.05±1.52 | 1.35±0.51 | 71.25±26.36 | |
17.5% GM rice | 5.34±0.42 | 128.25±7.94 | 43.56±2.85 | 81.69±4.39 | 24.10±1.56 | 294.75±9.22 | 375.13±63.77 | 9.14±0.54 | 1.25±0.43 | 66.50±20.13 | |
70% GM rice | 5.38±0.43 | 126.25±9.28 | 43.94±3.78 | 81.80±5.37 | 23.48±1.09 | 287.58±10.93 | 379.42±77.83 | 9.04±1.36 | 1.09±0.29 | 57.58±13.80 | |
Treatment Month 3 | Non-GM rice | 5.19±0.44 | 124.13±8.31 | 42.60±2.85 | 82.28±4.61 | 23.98±1.18 | 291.88±13.41 | 445.13±93.09 | 9.11±0.77 | 1.64±0.80 | 81.75±34.62 |
Positive control | 5.55±0.38 | 129.75±5.32 | 43.23±1.97 | 78.05±3.78 | 23.45±0.61 | 300.25±7.50 | 405.75±46.64 | 9.10±1.44 | 1.28±0.59 | 69.50±28.45 | |
17.5% GM rice | 5.32±0.38 | 124.25±11.06 | 42.15±3.14 | 79.33±4.76 | 23.38±1.68 | 294.75±8.84 | 425.50±78.18 | 9.01±0.59 | 1.23±0.27 | 58.25±22.79 | |
70% GM rice | 5.33±0.50 | 124.00±10.30 | 42.89±3.69 | 80.75±4.83 | 23.32±1.33 | 289.08±7.67 | 397.33±84.31 | 9.14±1.20 | 1.38±0.52 | 71.67±24.51 | |
Treatment Month 6 | Non-GM rice | 5.07±0.49 | 129.50±8.11 | 43.84±3.30 | 86.66±4.45 | 25.63±1.17 | 295.88±9.72 | 409.38±45.24 | 9.40±0.71 | 1.34±0.46 | 66.85±18.84 |
Positive control | 4.89±0.53 | 122.25±6.40 | 39.53±3.84 | 81.15±4.59 | 25.15±1.48 | 310.25±15.65 | 412.00±13.22 | 9.20±0.88 | 0.10±0.00** | 4.38±1.71** | |
17.5% GM rice | 5.33±0.56 | 133.50±12.95 | 44.86±4.39 | 84.31±5.48 | 25.13±1.69 | 297.88±11.05 | 424.50±95.20 | 9.10±0.85 | 1.09±0.40 | 57.58±18.92 | |
70% GM rice | 5.40±0.63 | 132.08±12.49 | 45.41±3.69 | 84.53±5.23 | 24.57±1.34 | 290/83±7.58 | 364.67±80.52 | 9.45±1.09 | 1.12±0.43 | 58.53±19.64 | |
Recovery | Non-GM rice | 4.55 | 123.00 | 39.90 | 87.65 | 26.95 | 307.50 | 343.00 | 9.45 | 1.10 | 49.50 |
Positive control | / | / | / | / | / | / | / | / | / | / | |
17.5% GM rice | 4.89±0.45 | 129.75±8.18 | 40.98±2.03 | 84.15±6.13 | 26.65±2.55 | 316.50±8.89 | 434.00±87.96 | 8.68±0.62 | 1.25±0.49 | 59.53±18.82 | |
70% GM rice | 5.48±0.87 | 137.50±11.09 | 44.73±3.36 | 82.50±7.18 | 25.38±2.47 | 307.50±7.42 | 327.00±81.18 | 8.65±1.01 | 1.03±0.56 | 52.73±23.10 |
Note: Data are presented as the mean±SD. During the quarantine period and the study period, there were 8, 4, 8 and 12 animals in the non-GM rice, positive control, 17.5% GM rice and 70% GM rice groups, respectively, whereas there were 2, 0, 4 and 4 animals in the four respective group during the recovery period.
*: Significantly different from the non-GM rice group at p<0.05.
**: Significantly different from the non-GM rice group at p<0.01.