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. 2016 Sep 29;11(9):e0164074. doi: 10.1371/journal.pone.0164074

Fig 6. Variable genomic region 1 and 2 (VGR-1, and -2) within L. pneumophila Philadelphia strains and additional ST36 genomes.

Fig 6

(A) VGR-1A is conserved in strain Philadelphia-1 (CDC) and in 19 of 22 additional ST36 strains, including strains C2-S, C3-O, C4-S, C5-P, C6-S, C7-O, C8-S, C9-S, C10-S, C11-O, E3-N, E4-N, E5-N, E6-N, E7-O, E8-O, E9-O, E10-P, E11-U, as well as L. pneumophila str. LPE509 and a sg12 strain (ATCC 43290), while VGR-1B is conserved in strains Philadelphia-2, -3, -4, E1-P, C1-S, and Paris. (B) VGR-2A is conserved in strain Philadelphia-1 (CDC) and in 21 of 22 additional ST36 strains, including C1-S, C2-S, C3-O, C4-S, C5-P, C6-S, C7-O, C8-S, C9-S, C10-S, C11-O, E2-N, E3-N, E4-N, E5-N, E6-N, E7-O, E8-O, E9-O, E10-P, and E11-U, while VGR-2B is conserved in strains Philadelphia-2, -3, -4, E1-P, and Paris. Solid grey strips, vertical, and horizontal black lines represent conserved sequence, SNPs, and sequence gaps, respectively, as in Fig 3. A Solid blue or green rectangle above the sequence delineates the boundaries of the VGR. Nucleotide boundaries and neighboring genes (in red) are relative to the genome immediately below these descriptions.