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. 2016 Sep 29;11(9):e0163272. doi: 10.1371/journal.pone.0163272

Fig 3. Refractile morphology of silent mutant cell lines was MAPK, but not PI3K, dependent.

Fig 3

Cells were plated at low density and photographed with phase contrast microscopy before or after 24 hours of treatment. Left column: vehicle only. Center column: Mek 1/2 inhibitor (1 μM trametinib). Right column: PI3K inhibitor (5 μM LY294002). Insets are 4X views.