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. 2016 Sep 29;11(9):e0163272. doi: 10.1371/journal.pone.0163272

Table 2. Single synonymous mutations changed KRAS expression, doubling times, and cell densities.

   Minimum Doubling Time (hr) KRAS Protein Expression* Maximum Cells (x 105)
WT 44.0 1.0 7.3
G12V 20.5 16.6 51.9
36 T->A 28.7 5.4 15.9
36 T->C 22.5 14.3 18.7
36 T->G 34.2 3.2 18.8
39 C->A 30.0 3.4 16.3
39 C->G 28.5 5.8 16.1
39 C->T 27.1 6.1 16.8
180 T->A 25.1 4.0 18.1
180 T->C 24.6 13.0 19.2
180 T->G 28.4 2.4 21.4

*Normalized to WT = 1.0