Table 5. Changes in Resting Metabolic Rate at the end of the 8-Week Intervention and after 24 Weeks of Unsupervised Follow-up ^{a, b}.

	Assessment Period
Outcome Variable and Group	Baseline	Week 8	Week 32	Week 8 - Baseline	p value	ES	Week 32 - Baseline	p value	ES	Week 32 – Week 8	p value	ES	p value for overall interaction
Unadjusted RMR (kcal/day)c
CR	1892.5 (67.7)	1719.3 (69.3)	1807.3 (72.2)	-173.2 (35.2)	<.001		-85.2 (39.0)	0.039		88.0 (22.2)	<.001
ADF	1640.1 (65.1)	1539.7 (66.8)	1567.2 (69.2)	-100.4 (34.1)	0.007		-72.9 (37.3)	0.063		27.5 (22.0)	0.223
CR - ADF	252.4 (93.9)	179.6 (96.2)	240.1 (100.0)	-72.8 (49.0)	0.151	0.62	-12.3 (54.0)	0.822	0.09	60.5 (31.3)	0.065	-0.81	0.096
Adjusted RMR (kcal/day)c, d
CR	1757.6 (37.0)	1646.0 (32.8)	1681.53 (18.6)	-111.6 (36.9)	0.006		-76.1 (35.9)	0.045		35.6 (22.4)	0.126
ADF	1689.0 (34.2)	1672.8 (33.5)	1659.8 (20.1)	-16.2 (36.6)	0.662		-29.2 (35.2)	0.416		-13.0 (22.5)	0.569
CR - ADF	68.6 (51.1)	-26.8 (48.1)	21.7 (29.8)	-95.4 (51.4)	0.076	0.77	-46.9 (49.7)	0.356	0.39	48.5 (31.8)	0.140	-0.64	0.140

^aLinear Mixed Effects model analysis with unstructured covariance was used to assess the efficacy of intervention on each outcome variable. Test of time by group interaction used to test the efficacy of intervention (see p value for overall interaction). Results are mean (SE). Significant p values (p <0.05) are indicated in bold. Effect size (ES) is calculated as (2 × t value)/√DF, where degrees of freedom (DF). Hand calculations for between- and within-group differences may not be equal to data shown because all data were rounded to 0.1 decimal place. For CR: n=12 for baseline and week 8; n=10 for week 32; For ADF: n=13 for baseline and week 8; n=11 for week 32; Non-missing observations: n = 71.

^bResting Metabolic Rate (RMR).

^cRMR results exclude 1 observation at week 32 for 1 subject in ADF because the value was physiologically implausible.

^dRMR results adjusted for Fat Free Mass (FFM) and Fat Mass (FM).