Figure 1.
Vascular responses subdivided by quartiles of anxiety symptom score (SCL-90-R mean scores for Q1 = 39; Q2 = 45; Q3 = 52; Q4 = 63). Left vertical axis shows forearm resistance vessel (FRV) function as change (%) in forearm blood flow (FBF) in response to the highest dose of each intra-arterial infusion of acetylcholine (30 μg/min), nitroprusside (10 μg/min) and verapamil (100 μg/min). Right vertical axis shows forearm conduit vessel function, as flow-mediated dilatation (FMD) of the brachial artery. FRV function, but not FMD nor nitroglycerin-mediated FMD (NTG), was significantly reduced in participants with elevated anxiety scores.