Table 1.
Participant Characteristics
| Atherosclerotic Participants |
Healthy Control Participants |
|||
|---|---|---|---|---|
|
| ||||
| Variable | Mean ±SD | N | Mean ±SD | n |
| Age, yrs | 68 ± 8 | 89 | 68 ± 8 | 54 |
| Males, n | 52 | 89 | 14 | 54 |
| CAD, n | 89 | 89 | 0 | 54 |
| PAD, n | 16 | 89 | 0 | 54 |
| Diabetes, % | 28.1 | 89 | 3.7 | 54 |
| Smoking, % | 28.7 | 87 | 2.4 | 54 |
| BMI, kg/m2 | 31 ± 7 | 89 | 28 ± 6 | 54 |
| Systolic BP, mm Hg | 140 ± 20 | 88 | 132 ± 15 | 52 |
| Heart rate, bpm | 61 ± 9 | 88 | 61 ± 11 | 52 |
| Triglycerides, mg/dl | 138.0 ± 67.6 | 89 | 100.4 ± 57.9 | 54 |
| HDL cholesterol, mg/dl | 50.4 ± 15.7 | 89 | 58.8 ± 17.9 | 53 |
| LDL cholesterol, mg/dl | 88.7 ± 29.8 | 88 | 102.7 ± 28.7 | 54 |
| Glucose, mg/dl | 112.8 ± 25.1 | 89 | 93.3 ± 9.2 | 52 |
| hsCRP, mg/dl | 4.4 ± 6.1 | 81 | 3.1 ± 3.8 | 53 |
| Anxiety, SCL-90-R T-score* | 49 ± 10 | 89 | 46 ± 9 | 54 |
| Depression, SCL-90-R T-score* | 56 ± 10 | 89 | 51 ± 10 | 54 |
| Forearm blood flow, ml/min/dl | 30 ± 39 | 78 | 33 ± 34 | 52 |
| FRV acetylcholine 30 response, % | 214 ± 137 | 89 | 225 ± 139 | 52 |
| FRV nitroprusside 10 response, % | 239 ± 125 | 89 | 236 ± 155 | 52 |
| FRV verapamil 100 response, % | 201 ± 102 | 89 | 229 ± 136 | 51 |
| Brachial artery diameter, mm | 4.3 ± 0.8 | 78 | 3.9 ± .8 | 52 |
| Flow-mediated dilatation, % | 6.9 ± 3.8 | 78 | 6.0 ± 3.6 | 52 |
| Nitroglycerin dilatation, % | 10.4 ± 10.9 | 79 | 13.7± 5.7 | 50 |
Note: CAD = coronary artery disease; PAD = peripheral arterial disease; BMI = body mass index; HDL = high density lipoprotein; LDL = low density lipoprotein; FRV = forearm resistance vessel.
*
normalized to a non-psychiatric population with a mean of 50, and SD of 10.