Table 2.
Atherosclerotic Participants | Healthy Control Participants | |||
---|---|---|---|---|
| ||||
Variable | Standardized β | p-value | Standardized β | p-value |
FMD | −0.065 | 0.56 | 0.133 | 0.35 |
NTG | −0.098 | 0.40 | −0.108 | 0.45 |
Acetylcholine | −0.302 | 0.004 | 0.129 | 0.36 |
Nitroprusside | −0.228 | 0.031 | 0.180 | 0.20 |
Verapamil | −0.285 | 0.007 | 0.114 | 0.43 |
Note: Measures of forearm conduit vessel function are flow-mediated dilatation (FMD; % change from baseline) of the brachial artery, as well as the nitroglycerine-mediated (NTG; % change from baseline) response. Measures of forearm resistance vessel function are change (%) in blood flow in response to intra-arterial infusion of acetylcholine (30 μg/min), nitroprusside (10 μg/min) and verapamil (100 μg/min). Standardized beta values represent the relationship between anxiety symptoms and vascular function, not adjusted for age, gender, depression and cardiovascular risk factors. Conduit vessel standardized beta values (FMD and NTG) are adjusted only for baseline brachial artery diameter.