Table 3.

Strength of the Association between Acetylcholine FRV response, Anxiety, Depression and Cardiovascular Risk Factors in Participants with Atherosclerosis

Risk Factor	Standardized β	p-value	% Reduction in β for anxiety
Anxiety	−0.302	0.004
Glucose	−0.180	0.08	7.28
HDL-c	0.265	0.009	3.31
LDL-c	−0.029	0.78	0.99
Body Mass Index	−0.494	<.001	42.05
hsCRP	−0.026	0.81	−10.26
Depression	0.017	0.91	−3.97
Number of Antihypertensives	0.014	0.90	−0.66
Presence of Beta-blockers	−0.126	0.22	0.0
Presence of ACE Inhibitors	−0.031	0.77	−0.66
Use of Calcium Channel Blockers	0.085	0.41	−2.65
Use of Statins	−0.001	0.99	0.0
Systolic Blood Pressure	0.008	0.48	−10.26
Smoking	0.10	0.34	2.65
Heart Rate	0.037	0.72	−0.33

Note: Beta values are for the relationship between acetylcholine FRV response and anxiety (first row), and between acetylcholine FRV response, anxiety and the other covariates (glucose, HDL, etc.). Beta reductions are expressed as the percent reduction in the standardized β from multivariate regression models; Anxiety remained significantly associated with resistance vessel response to acetylcholine in all models except for BMI where it approached significance; ACH = acetylcholine.