Table 4.
Weighted coefficients for variables associated with death–censored and overall transplant failure at 5 years in both the original Birmingham model and the Birmingham–Mayo model
Variable | Original Birmingham Model | New Birmingham–Mayo Histology–Based Model | ||||
---|---|---|---|---|---|---|
Transformation | Death-Censored Failure | Overall Transplant Failure | Transformation | Death-Censored Failure | Overall Transplant Failure | |
UACR, mg/mmol | Log scale | — | 0.666 | Log10 value | — | 0.3712 |
UACR, mg/mmol | Log scale −0.46 | 1.107 | — | Log10 value −46 | 0.5053 | — |
Serum albumin, g/L | (Value −40)/5 | — | −0.217 | (Value −40)/5 | — | 0.4000 |
eGFR, ml/min per 1.73 m2 | (Value −47)/10 | −0.297 | −0.206 | (Value −47)/10 | −0.3969 | −0.2367 |
eGFR2, (ml/min per 1.73 m2)2 | [(Value −47)/10]2 | 0.0711 | 0.0669 | [(Value −47)/10]2 | 0.0677 | 0.06613 |
Rejection | 1.038 | 0.550 | — | 0.2806 | 0.4988 | |
Black ethnicity | 1.324 | 1.095 | — | 0.7582 | — | |
Asian ethnicity | — | 1.039 | 0.653 | |||
Recipient age, yr | (Value −46)/10 | 0.138 | 0.00149 | (Value −46)/10 | −0.2366 | 0.1202 |
Recipient age, yr2 | [(Value −46)/10]2 | 0.204 | 0.187 | [(Value −46)/10]2 | — | 0.0858 |
UACR with rejection interaction | Log(UACR)2 −0.46 for rejection | −0.543 | — | Log10(UACR value) −0.46 for rejection | 0.5579 | — |
g Score | Value | 0.917 | 0.5985 | |||
ci Score | Value | 0.5074 | — |
Urinary albumin-creatinine ratio values <0.1 amended to 0.1 before logarithmic transformation. —, no value.