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Inhibition of Orai1 Ca2+ channel by shRNA or SKF96365 prevented renal fibrosis in mice with UUO. Representative images of Masson Trichrome staining of kidney sections from sham-operated, 7-day UUO, and 14-day UUO mice treated with (A–C) Ad‑GFP–shRNA, (D–F) Ad‑Orai1–shRNA, (G–I) vehicle PBS, or (J–L) SOC channel blocker SKF96365.
