Table 2.
Tested Variant | Conditioning Variant | Beijing Cohort, n=2067, 1185 Patients/882 Controls | Shanghai Cohort, n=1472, 722 Patients/750 Controls | Cohorts Combined, n=3539, 1907 Patients/1632 Controls | |||
---|---|---|---|---|---|---|---|
OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | ||
rs6677604 | None | 0.55 (0.42 to 0.72) | 1.4 × 10−5 | 0.71 (0.52 to 0.96) | 0.02 | 0.61 (0.50 to 0.75) | 1.6 × 10−6 |
rs6677604 | ΔCFHR3/CFHR1 | 1.20 (0.52 to 2.80) | 0.67 | 1.38 (0.59 to 3.21) | 0.46 | 1.25 (0.69 to 2.27) | 0.46 |
ΔCFHR3/CFHR1 | None | 0.51 (0.38 to 0.67) | 2.3 × 10−6 | 0.65 (0.48 to 0.90) | 8.3 × 10−3 | 0.56 (0.46 to 0.70) | 8.5 × 10−8 |
ΔCFHR3/CFHR1 | rs6677604 | 0.42 (0.18 to 1.02) | 0.05 | 0.48 (0.20 to 1.15) | 0.09 | 0.45 (0.25 to 0.84) | 0.01 |