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. 2016 Sep 7;14(4):3503–3508. doi: 10.3892/mmr.2016.5731

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Copyright: © Tae et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Masson's trichrome staining in the (A) sham- and MI-operated rats at (B) 7 and (C) 56 days after coronary artery ligation. Scale bar, 5 mm. The arrows indicate that the infarct wall of the left ventricle becomes thinned following MI, whereas hypertrophy is evident in the non-infarct wall. Collagen (asterisks) was observed in the infarct wall of the LV 3 days after MI and continued to accumulate with time. (D) At 56 days after MI, Masson's trichrome staining demonstrated that necrotic myocardium was replaced with collagen (asterisks) and myofibroblasts. Scale bar, 50 μm in (D). MI, myocardial infarction; LV, left ventricle.