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. 2016 Aug 8;14(4):3134–3144. doi: 10.3892/mmr.2016.5598

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Markers of malignant tumor. (A) S-100B and (B) MIA, were examined by RT-qPCR analysis on day 14. Reprogramming genes reduced the malignancy of the irNCs. (C) Analysis of YKL-40 by RT-qPCR analysis on day 14, the reprogrammed cells induced migration. (D) Analysis of h-BDNF by RT-qPCR analysis on day 4 showed the infected gene was expressed consistently. All data are expressed as the mean ± standard deviation. ^**P<0.01, ^##P<0.01. RT-qPCR, reverse transcription-quantitative polymerase chain reaction; MIA, melanoma inhibiting protein; YKL-40, chitinase 3-like 1; h-BDNF, human brain-derived neurotrophic factor.