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. 2016 Aug 24;14(4):3646–3654. doi: 10.3892/mmr.2016.5670

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Copyright: © Shen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Resveratrol promotes the proliferation of NSCs in a concentration-dependent manner following oxygen-glucose deprivation/reoxygenation injury. Flow cytometry revealed that, compared with the (A) Nor group, the ratio of NSCs in the S and G2/M phase were significantly decreased in the (B) Mod group and, compared with the Mod group, increased in the (C–E) Res groups and, compared with the (C and E) Res1 and Res20 groups, increased in the (D) Res5 group, peaking in the 5 μmol/l (Res5) group. ^▲P<0.05, vs. Nor group; ^ΔP<0.05 and ^#P<0.01, vs. Mod group; ^*P<0.05, vs. Res1 and Res20 groups. Data are presented as the mean ± standard deviation and were compared using one-way analysis of variance (n=3 for each group). NSCs, neural stem cells; Nor, normal; Mod, model; Res, resveratrol.