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Organ-specific localization of CLDN1, 2, 4 and 5 in canine duodenum, lung, liver and kidney, as detected by immunohistochemistry. (A) CLDN1, (B) CLDN2, (C) CLDN4 and (D) CLDN5 were detected only in the kidney. Boxes in the upper panels (magnification, ×200) are areas magnified in the lower panels (magnification, ×400). Organs for which no boxes are indicated are those that revealed no detectable staining. Arrows indicate positive staining.
