Table 1. Top 5 largest dysregulated miRNAs.

	24 hours			24 hours
	Viable/Air-only control			Viable/HIC
	Fold change	FDR		Fold change	FDR
mmu-miR-23b-3p	−16.47	0.11	mmu-miR-23b-3p	−12.08	0.16
mmu-miR-30c-5p	−10.58	0.11	mmu-miR-24-3p	−9.51	0.16
mmu-miR-24-3p	−10.44	0.12	mmu-miR-30c-5p	−9.06	0.16
mmu-miR-30b-5p	−7.65	0.11	mmu-miR-30b-5p	−6.83	0.16
mmu-miR-23a-3p	−6.95	0.11	mmu-miR-29a-3p	−6.60	0.21
mmu-miR-2137	10.23	0.11	mmu-miR-2137	7.11	0.16
mmu-miR-592-3p	9.11	0.02*	mmu-miR-677-3p	6.43	0.16
mmu-miR-677-3p	8.84	0.11	mmu-miR-1843b-3p	6.23	0.16
mmu-miR-1947-3p	6.44	0.11	mmu-miR-1947-3p	5.91	0.16
mmu-miR-1843b-3p	6.40	0.11	mmu-miR-592-3p	5.67	0.12

	48 hours			48 hours
	Viable/Air-only control			Viable/HIC
	Fold change	FDR		Fold change	FDR
mmu-miR-23b-3p	−62.23	0.00*	mmu-miR-23b-3p	−52.84	0.00*
mmu-miR-24-3p	−34.34	0.00*	mmu-miR-24-3p	−32.66	0.00*
mmu-miR-23a-3p	−25.30	0.01*	mmu-miR-29a-3p	−22.03	0.01*
mmu-miR-30c-5p	−24.90	0.00*	mmu-miR-23a-3p	−21.05	0.01*
mmu-miR-29a-3p	−20.97	0.01*	mmu-miR-30c-5p	−21.05	0.00*
mmu-miR-677-3p	15.98	0.00*	mmu-miR-2137	13.14	0.00*
mmu-miR-2137	15.35	0.00*	mmu-miR-677-3p	12.42	0.00*
mmu-miR-1947-3p	13.52	0.01*	mmu-miR-1947-3p	11.39	0.01*
mmu-miR-1843b-3p	13.30	0.00*	mmu-miR-1843b-3p	10.64	0.00*
mmu-miR-3103-3p	12.69	0.00*	mmu-miR-3103-3p	10.22	0.00*

^*p-value ≤ 0.05 is considered significant.

FDR = False discovery rate.