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. Author manuscript; available in PMC: 2017 Mar 12.
Published in final edited form as: Nat Genet. 2016 Sep 12;48(10):1171–1184. doi: 10.1038/ng.3667

Figure 2. Enrichment of DNAse hypersensitive sites among BP loci in different cell-types.

Figure 2

Enrichment analyses of SBP or DBP associated loci according to discovery P value using narrow peaks (panel A) or broad peaks (panel B). SNPs were selected according to different P value cutoffs (x-axis) and a fold enrichment of overlap with DNAse hypersensitive sites compared to unrelated GWAS SNPs was calculated (y-axis) (see Supplementary Note). The 12 endothelial cell-lines are indicated in color and for each endothelial cell-type the rank using the 10−14 P value cutoff is indicated. EC denotes endothelial cells.