Table 1.
Preoperative and demographic characteristics of neonates requiring arterial switch operation for transposition of the great arteries in the period 2004–2010
| Variables | Total N = 91 n (%) |
Ventricular septal defect | p value | |
|---|---|---|---|---|
| No VSD N = 60 n (%) |
VSD N = 31 n (%) |
|||
| Demographic and birth characteristics | ||||
| Male | 61 (67 %) | 38 (63 %) | 23 (74 %) | 0.30 |
| Antenatal diagnosis: yes | 27 (30 %) | 17 (28 %) | 10 (32 %) | 0.70 |
| Birth gestation (weeks) | 39.0 (1.8) | 39.1 (1.9) | 38.8 (1.5) | 0.60 |
| Birth weight (g) | 3367.6 (569) | 3370.1 (597) | 3363.0 (517) | 0.96 |
| Apgar at 5 min | 8.1 (1.2) | 7.9 (1.3) | 8.3 (0.9) | 0.24 |
| Socioeconomic index (Blishen) | 46.3 (13.9) | 45.6 (12.9) | 47.7 (15.8) | 0.50 |
| Total years of mother’s schooling | 14.1 (3.3) | 13.6 (2.9) | 15.1 (3.9) | 0.06 |
| Guardianship | ||||
| Parents | 81 (89 %) | 52 (87 %) | 29 (94 %) | |
| Mother | 6 (7 %) | 4 (7 %) | 2 (6 %) | |
| Father | 1 (1 %) | 1 (2 %) | 0 (0 %) | |
| Other | 3 (3 %) | 3 (5.0 %) | 0 (0 %) | 1.00 |
| Race | ||||
| European/white | 70 (84 %) | 45 (80 %) | 25 (93 %) | |
| Original peoples | 2 (2 %) | 2 (4 %) | 0 (0 %) | |
| Other | 11 (13 %) | 9 (16 %) | 2 (7 %) | 0.32 |
| Delivery at hospital outside of the region of the operating site | 60 (66 %) | 44 (73 %) | 16 (52 %) | 0.04 |
| Preoperative characteristics | ||||
| Pre-operative septostomy | 66 (73 %) | 48 (80 %) | 18 (58 %) | 0.03 |
| Modified inotrope score | 7.7 (9.7) | 7.5 (9.8) | 8.1 (9.6) | 0.78 |
| Plasma lactate (mmol/L) | 3.4 (3.1) | 3.3 (3.3) | 3.6 (2.7) | 0.65 |
| Days ventilated (days) | 5.3 (4.7) | 5.2 (3.1) | 5.5 (6.9) | 0.85 |
| Highest serum creatinine (μmol/L) | 62.6 (19.1) | 62.2 (17.1) | 63.3 (22.8) | 0.80 |
| Sepsis (blood culture confirmed) | 3 (3 %) | 3 (5 %) | 0 | 0.55 |
| Hydrocortisone cumulative exposure (mg/kg) | 4.2 (12.8) | 4.8 (14.8) | 3.1 (7.7) | 0.49 |