Table 2.
Perioperative characteristics of neonates who required arterial switch operation for transposition of the great arteries in the period 2004 to 2010
| Variables | Total N = 91 n (%) |
Ventricular septal defect | p value | |
|---|---|---|---|---|
| No VSD N = 60 n (%) |
VSD N = 31 n (%) |
|||
| Operative | ||||
| Year at surgery | 2007.3 (2.2) | 2007.3 (1.9) | 2007.4 (2.6) | 0.80 |
| Age at surgery (days) | 11.5 (14.8) | 9.1 (3.8) | 16.2 (24.4) | 0.12 |
| Weight at surgery (kg) | 3.485 (0.669) | 3.445 (0.607) | 3.562 (0.781) | 0.43 |
| Cardiopulmonary bypass time (min) | 120.6 (39.8) | 116.8 (32.9) | 128.0 (50.3) | 0.27 |
| Cross-clamp time (min) | 66.5 (18.5) | 62.7 (14.0) | 73.9 (23.6) | 0.02 |
| Use of deep hypothermic circulatory arrest | 60 (66 %) | 42 (70 %) | 18 (58 %) | 0.26 |
| Need for re-cardiopulmonary bypass during first OR | 7 (8 %) | 3 (5 %) | 4 (13 %) | 0.22 |
| Post-operative, day 1 | ||||
| Modified inotrope score | 8.7 (7.2) | 8.5 (7.5) | 9.1 (6.8) | 0.70 |
| Plasma lactate (mmol/L) | 4.2 (1.6) | 3.9 (1.6) | 4.8 (1.5) | 0.01 |
| Time for lactate to return to 2 or less (h) | 10.9 (8.4) | 10.3 (8.9) | 12.0 (7.3) | 0.36 |
| Highest serum creatinine (μmol/L) | 51.5 (12.3) | 50.3 (11.9) | 53.8 (13.0) | 0.19 |
| Post-operative, day 2–5 | ||||
| Modified inotrope score | 7.7 (7.7) | 7.1 (6.7) | 8.7 (9.3) | 0.41 |
| Plasma lactate (mmol/L) | 2.2 (1.1) | 2.2 (1.2) | 2.3 (0.8) | 0.82 |
| Serum creatinine (μmol/L) | 61.5 (22.2) | 61.5 (24.3) | 61.3 (17.9) | 0.97 |
| Post-operative, day 6+ | ||||
| Modified inotrope score | 1.2 (2.6) | 1.2 (2.6) | 1.4 (2.6) | 0.74 |
| Plasma lactate (mmol/L) | 1.1 (0.4) | 1.1 (0.35) | 1.2 (0.49) | 0.21 |
| Serum creatinine (μmol/L) | 47.0 (20.7) | 45.2 (20.9) | 50.4 (20.3) | 0.26 |
| All post-operative time | ||||
| Ventilation (days) | 6.2 (3.5) | 6.0 (3.5) | 6.7 (3.4) | 0.38 |
| Admission to PICU (days) | 10.8 (5.0) | 10.5 (4.9) | 11.4 (5.2) | 0.37 |
| Overall/any time | ||||
| All hospital days (SCH) | 19.1 (8.4) | 18.1 (8.3) | 21.0 (8.4) | 0.12 |
| Convulsions | 6 (7 %) | 2 (4 %) | 3 (14 %) | 0.41 |
| Ventilation (days) | 11.0 (5.5) | 11.1 (5.4) | 10.7 (5.7) | 0.73 |
| Sepsis pre or post-operative (blood culture positive) | 7 (8 %) | 3 (6 %) | 3 (10 %) | 0.42 |
| Dialysis | 4 (4 %) | 1 (2 %) | 3 (10 %) | 0.11 |
| Dialysis or creatinine >100 (μmol/L) | 11 (12 %) | 4 (7 %) | 7 (23 %) | 0.04 |