Table 2.
Effects of atorvastatin on the markers of chronic inflammation, oxidative stress, and telomerase activity.
| Atorvastatin (n = 44) | Without treatment (n = 38) | p1 | ||
|---|---|---|---|---|
| CRP, mg/L, | Baseline | 5.3 ± 0.9 | 3.3 ± 0.7 | 0.1 |
| M ± m | 12 months | 4.5 ± 0.1 | 3.0 ± 0.1 | |
| p2 | 0.520 | 0.721 | ||
| FBG, g/L, | Baseline | 3.60 ± 0.10 | 3.26 ± 0.06 | 0.021 |
| M ± m | 12 months | 3.51 ± 0.10 | 3.21 ± 0.07 | |
| p2 | 0.519 | 0.711 | ||
| IL-6, pg/mL, | Baseline | 3.64 ± 0.92 | 5.93 ± 1.91 | 0.56 |
| M ± m | 12 months | 6.73 ± 1.04 | 8.12 ± 3.21 | |
| p2 | 0.021 | 0.559 | ||
| MDA, mcmol/L, | Baseline | 3.1 ± 0.1 | 3.0 ± 0.1 | 0.596 |
| M ± m | 12 months | 3.3 ± 0.1 | 3.4 ± 0.2 | |
| p2 | 0.244 | 0.086 | ||
| Blood urea, | Baseline | 6.1 ± 0.2 | 5.6 ± 0.2 | 0.139 |
| mmol/L, M ± m | 12 months | 5.5 ± 0.8 | 5.3 ± 0.2 | |
| p2 | 0.082 | 0.37 |
CRP, C-reactive protein; FBG, fibrinogen; IL-6, interleukin 6; MDA, malondialdehyde; M ± m, mean ± standard error of the mean; p1, p-value for independent groups, p2, p-value for dependent groups.