Table. 2. Hematological parameters measured in the female Wistar rats.
Parameters | Control | 250 mg/kg | 500 mg/kg | 1,000 mg/kg |
---|---|---|---|---|
WBC (103/μL) | 3.6 ± 0.25 | 6.63 ± 0.12 | 2.17 ± 0.23 | 2.33 ± 0.12 |
RBC (106/μL) | 5.38 ± 0.03 | 6.5 ± 0.15 | 4.69 ± 0.09 | 5.5 ± 0.15 |
HB (g/dL) | 10.9 ± 0.11 | 13.13 ± 0.9 | 10.77 ± 0.19 | 11.03 ± 0.09 |
HCT (%) | 33.1 ± 0.7 | 37.73 ± 0.27 | 30.83 ± 1.34 | 33.53 ± 0.89 |
MCV (fL) | 60.43 ± 0.49 | 55.43 ± 0.41 | 59.77 ± 0.26 | 56.97 ± 1.02 |
MCH (pq) | 21.3 ± 0.46 | 20.27 ± 0.49 | 21.33 ± 0.26 | 19.9 ± 0.47 |
MCHC (g/dL) | 34.8 ± 0.21 | 35.93 ± 0.20 | 35.83 ± 0.29 | 34.83 ± 0.23 |
PLT (103/μL) | 100.33 ± 2.60 | 86.33 ± 1.45‡ | 74.67 ± 1.45‡ | 67.33 ± 0.67 |
LYMP (%) | 2.93 ± 0.09 | 4.53 ± 0.12 | 2.07 ± 0.26 | 2 ± 0.06 |
Values are expressed as means ± SEMs (number of animals, n = 6); and were significantly different at *P < 0.05, †P < 0.01, and ‡P < 0.001, when compared with the control group. SEMs, standard errors of the mean; WBC, white blood cell; RBC, red blood cell, HB, haemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular haemoglobin; MCHC, mean corpuscular hemoglobin concentration; PLT, platelets; LYMP, lymphocyte.