Figure 1.

Effect of curcumin on PC cell growth, apoptosis, and cell cycle. A. Effect of curcumin on PC cells growth was detected by CTG assay after treatment with curcumin for 48 and 72 h. *P < 0.05, **P < 0.01, compared to the control groups (DMSO treatment). B. Left panel, Colony formation viability of PC cells treated with curcumin was evaluated by clonogenic assay. Right panel, quantitative results are illustrated for left panel. *P < 0.05, **P < 0.01 vs control. X axis: concentrations of curcumin. Y axis: percentage of colony numbers in control groups. C. Cell apoptosis in PC cells treated with curcumin was accessed by Flow cytometry. D. Curcumin induced PC cell cycle arrest at G2-M Phase.