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. 2016 Sep 1;6(9):1949–1962.

Figure 5.

Figure 5

Knockdown of Skp2 inhibited cell proliferation and invasion and facilitated cell apoptosis. A: The effect of down-regulated Skp2 in combination with curcumin treatment on PC cell growth was detected by CTG assay. Control: control siRNA; siRNA: Skp2 siRNA; Both: Skp2 siRNA+Curcumin. *P < 0.05, **P < 0.01, compared with control; #P < 0.05 compared with curcumin treatment or Skp2 siRNA transfection. B: Cell apoptosis was accessed by Flow cytometry in PC cells treated with Skp2 siRNA and curcumin. C. Left panel, PC cells invasion was detected after Skp2 siRNA transfection and curcumin treatment. Right panel, Quantitative results are illustrated for left panel. *P < 0.05, **P < 0.01, compared with control; #P < 0.05 compared with curcumin treatment or Skp2 siRNA transfection.