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. 2016 Sep 1;6(9):1996–2009.

Figure 5.

Figure 5

miR-302b inhibitor restored ephrin-A1-mediated cell death in MMCs. MMC apoptosis was determined by Annexin V apoptosis detection assay, wherein Control is untreated MMCs and Sc-control is MMC transfected with scrambled miRNA. miR-302b inhibitor restored ephrin-A1-mediated apoptosis in MMC. MMCs were transfected with or without miR-302b and miR-302b inhibitor and treated with or without ephrin-A1 and apoptosis was determined (A). MMCs were transfected with or without Mcl-1 siRNA and miR-302b and treated with or without ephrin-A1 as shown and apoptosis was determined (B). Date presented is the representatives of three independent observations performed at different times. The values *p < 0.05 as compared to control; and $p < 0.05 as compared to miR-302b alone; **p < 0.05 as compared to con-siRNA; and NS = not significant when compared to Mcl-1-siRNA alone.