Table 7.
Frequency of acute toxicities from CCRT by type and grade
| Toxicity | Experimental group n (%) | control group n (%) | z | p | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| 0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | |||
| Neutropenia | 5 (4.4) | 20 (17.7) | 38 (33.6) | 44 (38.9) | 6 (5.3) | 5 (4.6) | 27 (25.0) | 45 (41.7) | 28 (25.9) | 3 (2.8) | 2.203 | 0.028 |
| Anemia | 59 (52.2) | 35 (31.0) | 12 (10.6) | 5 (4.4) | 2 (1.8) | 30 (27.8) | 32 (29.6) | 26 (24.1) | 15 (13.9) | 5 (4.6) | 4.475 | 0.0001 |
| Thrombocytopenia | 38 (33.6) | 35 (31.0) | 19 (16.8) | 18 (15.9) | 3 (2.7) | 51 (47.2) | 29 (26.9) | 15 (13.9) | 11 (10.2) | 2 (1.9) | 2.107 | 0.035 |
| Vomiting | 2 (1.8) | 7 (6.2) | 48 (42.5) | 56 (49.6) | 0 (0) | 0 (0) | 2 (1.9) | 38 (35.2) | 68 (63.0) | 0 (0) | 2.270 | 0.023 |
| Hepatotoxicity | 87 (77.0) | 22 (19.5) | 4 (3.5) | 0 (0) | 0 (0) | 79 (73.1) | 24 (22.2) | 5 (4.6) | 0 (0) | 0 (0) | 0.675 | 0.500 |
| Nephrotoxic | 110 (97.3) | 3 (2.7) | 0 (0) | 0 (0) | 0 (0) | 104 (96.3) | 4 (3.7) | 0 (0) | 0 (0) | 0 (0) | 0.444 | 0.657 |
| Mucositis | 0 (0) | 18 (15.9) | 62 (54.9) | 33 (29.2) | 0 (0) | 0 (0) | 15 (13.9) | 57 (52.8) | 36 (33.3) | 0 (0) | 0.701 | 0.483 |
| Dermatitis | 2 (1.8) | 82 (72.6) | 24 (21.2) | 5 (4.4) | 0 (0) | 4 (3.7) | 75 (69.4) | 25 (23.1) | 4 (3.7) | 0 (0) | 0.082 | 0.935 |
| Xerostomia | 3 (2.7) | 24 (21.2) | 84 (74.3) | 2 (1.8) | 0 (0) | 3 (2.8) | 21 (19.4) | 82 (75.9) | 2 (1.9) | 0 (0) | 0.278 | 0.781 |