Table 3.
Univariate and multivariable Cox proportional hazards regression: risk of mortality (60 aspirin users vs. 60 matched)
| Characteristics | Univariate P | Multivariate P | HR (95% CI) |
|---|---|---|---|
| Aspirin usage | 0.050* | 0.066 | 0.604 (0.354-1.033) |
| Age (≤ 65 y/> 65 y) | 0.957 | 0.387 | 1.301 (0.717-2.363) |
| Gender (male/female) | 0.203 | 0.193 | 0.637 (0.323-1.257) |
| Underlying liver disease | |||
| TB (≤ 3 mg/> 3 mg) | 0.014* | 0.091 | 2.253 (0.879-5.771) |
| GGT (≤ 75 µL/> 75 µL) | 0.000* | 0.006* | 2.327 (1.268-4.272) |
| PLT (≤ 100 × 109/L /> 100 × 109/L) | 0.880 | ||
| Anti-HBV treatment | 0.246 | ||
| Cirrhosis | 0.918 | ||
| Tumor characteristics at initial TACE | |||
| Tumor size (≤ 5 cm/> 5 cm) | 0.000* | 0.094 | 1.757 (0.908-3.402) |
| Tumor number (solitary/multiple) | 0.993 | 0.579 | 0.805 (0.373-1.733) |
| Vascular invasion (without/with) | 0.194 | 0.071 | 2.393 (0.929-6.161) |
| Combined treatment | |||
| Hepatic resection (with/without) | 0.093 | 0.210 | 0.547 (0.214-1.403) |
| RFA (with/without) | 0.103 | 0.767 | 0.908 (0.479-1.720) |
Abbreviations: TB, total bilirubin; GGT, gamma-glutamyl transferase; PLT, platelet; AFP, alpha-fetoprotein; RFA, radiofrequency ablation.
*
P < 0.05.