Figure 7. MiR-19b regulates ureagenesis in pig primary hepatocytes.
(A) Urea concentration in hepatocytes treated with miR-19b mimic, inhibitor, or negative control. Data are presented as mean ± SD (*P < 0.05, **P < 0.01, n = 6). (B) Western blot results showed that SIRT5 protein and CPS1 protein expression in primary hepatocytes was significantly decreased by miR-19b mimic versus control; miR-19b inhibitor rescued this effect. Data are presented as mean ± SD (*P < 0.05, n = 6).