Table 1.
Hematologic, serum and anthropometrical parameters, including heart rate, VO2peak and RRtHb
| Study week |
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D | 1 | 2 | 3 | 4 | 6 | 7 | 10 | 13 | 18 | 22 | 26 | 33 | 45 | 58 | 71 | 91 | |
| tHb, g | – | 847 | 828 | 760 | 718 | 794 | 766 | 842 | 795 | 875 | 854 | 810 | 826 | 900 | 901 | – | 837 |
| [Hb], g/dl | 15.1 | 15.7 | 14.6 | 13.6 | 14.1 | 15.1 | 15.1 | 15.4 | 15.1 | 15.8 | 15.2 | 15.4 | 15.0 | 16.1 | 16.4 | 15.8 | 14.4 |
| Hematocrit, % | 42.9 | 45 | 42.1 | 40.0 | 40.5 | 42.1 | 41.8 | 43.7 | 42.0 | 43.7 | 42.4 | 43.4 | 42.0 | 44.2 | 44.9 | 43.0 | 42.8 |
| MCV, fl | 91.6 | 91.2 | 91.5 | 92.2 | 92.0 | 91.5 | 91.3 | 91.6 | 90.9 | 89.4 | 90.4 | 90.0 | 88.8 | 90.6 | 89.3 | 89.4 | 91.6 |
| MCH, pg | 32.2 | 31.8 | 31.7 | 31.4 | 32.1 | 32.8 | 33.0 | 32.3 | 32.7 | 32.3 | 32.4 | 32.0 | 31.7 | 33.0 | 32.6 | 32.8 | 30.8 |
| MCHC, g/dl | 35.2 | 34.6 | 34.1 | 34.8 | 35.9 | 36.1 | 35.2 | 36.0 | 36.2 | 35.8 | 35.5 | 35.7 | 36.4 | 36.5 | 36.7 | 36.7 | 33.6 |
| Reticulocytes, % | – | 1.44 | 1.54 | – | 2.41 | 1.81 | 2.18 | – | 1.17 | 0.98 | 1.44 | 1.51 | 0.91 | 1.46 | 1.72 | – | 1.90 |
| TF saturation, % | 58 | – | 32 | 37 | – | – | 31 | – | 27 | – | – | 28 | 24 | 36 | – | – | 30 |
| GPT, U/l | 95 | 75 | – | – | – | 45 | – | – | 39 | – | – | – | 36 | 37 | – | – | 48 |
| hsCRP, mg/1 | 2.66 | 2.15 | – | – | – | – | – | – | – | – | 3.51 | 1.62 | – | 4.76 | 4.76 | 2.42 | – |
| Body weight, kg | 86.6 | 83.7 | 80.5 | 80.5 | 79.1 | 80.0 | 80.5 | 79.6 | 81.1 | 81.0 | 80.7 | 81.9 | 80.8 | 82.5 | 83.6 | 83.0 | 84.6 |
| LBM, kg | 61.9 | – | – | – | – | – | – | – | – | 62.1 | – | – | – | – | – | 59.7 | – |
| BMI | 26.1 | 26.1 | 25.1 | 25.1 | 24.7 | 25 | 25.1 | 24.6 | 25.3 | 25.3 | 25.2 | 25.3 | 25.1 | 25.6 | 25.9 | 25.9 | 26.3 |
| Resting HR, 1/min | 57 | 52 | 56 | 56 | 56 | 52 | 52 | – | 60 | – | – | – | – | – | – | – | 57 |
| VO2peak, ml/min/kg | 49.8 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 49.8 |
| RRtHb, g/day | – | – | 8.5 | 0.7 | 3.7 | 10.4 | 6.7 | 10.8 | 5.1 | 6.6 | 4.9 | 3.9 | 0.3 | 1.8 | 0.0 | – | – |
D = Day of diagnosis; TF saturation = transferrin saturation; LBM = lean body mass; resting HR = resting heart rate; RRtHb = reproduction rate of tHb, definition see case presentation and methods.