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. 2016 Sep 30;7:1566. doi: 10.3389/fmicb.2016.01566

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Copyright © 2016 Chen, Fang, Zhou, Zhang, Shi and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A heat-map showing the changes of Salmonella isolates after plasmid curing based on antibiotic resistance profiles as well as plasmid replicon type(s). “C” denoted the cured variant. Black and white squares denotes the presence and absence of a particular feature, respectively. The antibiotics listed are abbreviated as follows: AMP, ampicillin; TZP, piperacillin/tazobactam; SAM, ampicillin/sulbactam; CRO, ceftriaxone; CAZ, ceftazidime; ATM, aztreonam; CZO, cephazolin; CIP, ciprofloxacin; AMK, amikacin; GEN, gentamicin; TOB, tobramycin; LEV, levofloxacin; SXT, sulfamethoxazole/trimethoprim.