Table 3.

Effect on postoperative VAS, facial, and behavioural pain scale score, mean ± SD

Drugs group (n = 90)	Time in hours
	0	1	2	4	6	24
Control group (Diclofenac 100 mg)
VAS	2.3±0.5	3.4±0.4	4.7±0.6	4.3±0.9	4±0.3	2.3±0.4
FRS	2.3±0.5	3.6±0.5	4.3±0.3	3.7±0.4	4±0.4	2.3±0.5
BRS	2.3±0.5	3.2±0.4	4.2±0.5	3.1±0.3	4±0.3	2.3±0.4
ADRs	Nausea = 4	Vomiting = 13
Test group 1 (Topiramate 200 mg)
VAS	2.5±0.5	3.9±0.5*, †	4.8±0.3†	4.0±0.2	4±0.4	2.5±0.4
FRS	2.5±0.5	3.8±0.5†	4.6±0.5†	3.5±0.3	4±0.5	2.5±0.5
BRS	2.5±0.5	3.7±0.5*, †	4.5±0.5†	3±0.2	4±0.2	2.5±0.5
ADRs	Nausea = 8	Vomiting = 18
Test group 2 (Lamotrigine 100 mg)
VAS	2±0.3	3±0.3*	4.1±0.4*	4±0.2	3.3±0.6	2±0.1
FRS	2±0.2	3.2±0.5*	4±0.2	4±0.4	3.2±0.4	2±0.2
BRS	2±0.2	3.2±0.5	4.1±0.4	3.8±0.4	3.2±0.4	2±0.2
ADRs	Nausea = 2	Vomiting = 8

^*p< 0.05 compared to control.

^†p< 0.05 compared to Lamotrigine.

ADR = Adverse drug reaction.