Table 2. Correlations of IHC staining score of alpha-1 antitrypsin and H2B1K with clinical parameters.
IHC staining | Normal versus UC | p value | |||
---|---|---|---|---|---|
Normal (26) | UC (122) | ||||
Alpha-1-antirtypsin | 55.48 | 78.55 | 0.002* | ||
H2B1K | 54.13 | 78.84 | 0.007* | ||
Age | |||||
<65 (19) | ≥65 (103) | ||||
Alpha-1-antirtypsin | 54.89 | 62.72 | 0.299 | ||
H2B1K | 57.47 | 62.24 | 0.587 | ||
Grade | |||||
Low (46) | High (76) | ||||
Alpha-1-antirtypsin | 51.73 | 67.41 | 0.005* | ||
H2B1K | 70.01 | 56.35 | 0.037* | ||
Tumor size | |||||
<1 cm (61) | 1–3 cm (43) | ≥3 cm (18) | |||
Alpha-1-antirtypsin | 53.01 | 60.78 | 92 | <0.001* | |
H2B1K | 62.28 | 62.29 | 56.03 | 0.773 | |
Number of tumors | |||||
Single (72) | Multiple (49) | ||||
Alpha-1-antirtypsin | 64.41 | 55.99 | 0.129 | ||
H2B1K | 61.17 | 60.74 | 0.947 | ||
T | |||||
Ta + Tis | T1 + T2 | T3 + T4 | |||
Alpha-1-antirtypsin | 49.88 | 62.94 | 61.48 | 0.512 | |
H2B1K | 94.25 | 56.13 | 63.43 | 0.013* | |
N | |||||
N0 (117) | N1 (2) | N2 (2) | |||
Alpha-1-antirtypsin | 59.97 | 70.25 | 111.75 | 0.046 | |
H2B1K | 60.75 | 70.5 | 66.0 | 0.907 | |
M | |||||
M0 (117) | M1 (5) | ||||
Alpha-1-antirtypsin | 60.43 | 86.6 | 0.057 | ||
H2B1K | 62.9 | 28.7 | 0.033* | ||
Stage | |||||
0 (7) | I + II (64) | III (38) | IV (13) | ||
Alpha-1-antirtypsin | 51.29 | 61.13 | 56.07 | 84.69 | 0.021* |
H2B1K | 95.64 | 58.06 | 62.01 | 58.54 | 0.062 |