Table 1.
Baseline characteristics of MTHFR risk, MTHFR non-risk and control groups
| Demographical information | MTHFR Risk (CT/TT) (n = 178) | MTHFR Non-risk (CC) (n = 141) | Control (n = 309) | p valuea |
|---|---|---|---|---|
| Age (years) | 42 ± 13 | 41 ± 14 | 40 ± 13 | 0.526 |
| Gender (M/F) | 71/107 | 68/73 | 130/179 | 0.304 |
| Weight (kg) | 75.1 ± 15.4 | 76.5 ± 16.1 | 73.77 ± 15.02 | 0.216 |
| BMI (kg/m2) | 25.5 ± 4.9 | 26.0 ± 5.0 | 25.1 ± 4.4 | 0.138 |
| W.C. (m) | 0.86 ± 0.13 | 0.88 ± 0.14 | 0.85 ± 0.13 | 0.129 |
| Frequency % (n)b | ||||
| Germany | 19.1 (34) | 7.8 (11) | 0.010 | |
| Greece | 17.4 (31) | 13.5 (19) | ||
| Ireland | 10.7 (19) | 17.1 (24) | ||
| Netherlands | 16.3 (29) | 17.7 (25) | ||
| Poland | 8.4 (15) | 15.6 (22) | ||
| Spain | 16.3 (29) | 11.3 (16) | ||
| UK | 11.8 (21) | 17.0 (24) | ||
Excludes drop-outs at months 3 and 6
W.C. waist circumference
aBaseline characteristics presented as means ± standard deviations and differences between the groups were investigated using ANOVA for all variables with the exception of gender and country where chi-square analysis was used
bFrequency of country was assessed across the MTHFR risk and MTHFR non-risk groups only