Table 2.

Comparison of dietary intakes for the MTHFR risk, MTHFR non-risk and control groups at M0 and M6

	MTHFR risk (CT/TT)	Number	MTHFR non-risk (CC)	Number	Control	Number	p valuea
Energy (kJ) M0	10,201 ± 3423	178	11,558 ± 5479	141	10,617 ± 4810	309	0.203
M6	8810 ± 2968	178	9637 ± 3675	141	9605 ± 4132	309
Folate (μg per 10 MJ) M0	412 ± 172	178	391 ± 190	141	410 ± 186	309	0.131
M6	427 ± 193	178	410 ± 168	141	410 ± 210	309
Liver (g) M0	1 ± 3	178	2 ± 9	141	1 ± 3	309	0.162
M6	1 ± 4	178	1 ± 4	141	1 ± 3	309
Poultry (g) M0	33 ± 42	144	37 ± 40	130	30 ± 29	270	0.136
M6	33 ± 32	144	32 ± 28	130	32 ± 52	270
Shellfish (g) M0	4 ± 7	178	3 ± 7	141	3 ± 5	309	0.430
M6	4 ± 7	178	3 ± 6	141	3 ± 7	309
Green leafy veg (g) M0	49 ± 41	178	48 ± 44	141	45 ± 42	309	0.220
M6	53 ± 50	178	49 ± 45	141	46 ± 48	309
Fortified cereals (g) M0	22 ± 33	178	20 ± 31	141	19 ± 27	309	0.444
M6	22 ± 30	178	20 ± 24	141	20 ± 26	309
Beans and legumes (g) M0	22 ± 34	144	27 ± 34	130	25 ± 44	270	0.726
M6	20 ± 23	144	26 ± 48	130	21 ± 31	269

Excludes drop-outs at months 3 and 6

M0 month 0, M6 month 6

^aValues presented as means ± standard deviations. All analysis was conducted on log-transformed values. General linear models were used to assess the impact of group on month 6 intake with M0 as a covariate and controlling for country where necessary