Table 4.

Dietary intakes by MTHFR risk and MTHFR non-risk participants who were told to increase their folate intake compared with those who received general healthy eating advice (control group)

	MTHFR risk (CT/TT)	Number	MTHFR non-risk (CC)	Number	Control	Number	p valuea
Energy (kJ) M0	8620 ± 2708	83	8939 ± 2879	55	10,617 ± 4810	309	0.061
M6	7767 ± 2742	83	7842 ± 2237	55	9605 ± 4132	309
Folate (μg per 10 MJ) M0	361 ± 123	83	329 ± 81	55	410 ± 186	309	0.165
M6	385 ± 147	83	395 ± 175	55	410 ± 210	309
Liver (g) M0	1 ± 3	83	2 ± 4	55	1 ± 3	309	0.369
M6	2 ± 4	83	1 ± 4	55	1 ± 3	309
Poultry (g) M0	36 ± 53	66	27 ± 30	50	30 ± 29	270	0.072
M6	35 ± 28	66	25 ± 25	50	32 ± 55	270
Shellfish (g) M0	3 ± 6	83	3 ± 6	55	3 ± 5	309	0.092
M6	2 ± 3	83	2 ± 5	55	3 ± 7	309
Green leafy veg (g) M0	39 ± 38	83	38 ± 40	55	45 ± 42	309	0.261
M6	44 ± 33	83	42 ± 35	55	46 ± 48	309
Fortified cereals (g) M0	14 ± 19	83	11 ± 16	55	19 ± 27	309	0.469
M6	17 ± 21	83	14 ± 16	55	20 ± 26	308
Beans and legumes (g) M0	17 ± 17	66	19 ± 24	50	25 ± 44	270	0.146
M6	22 ± 22	66	27 ± 64	50	21 ± 31	269

Includes participants who were specifically advised to increase their folate intakes at month 0 and/or month 3 and where drop-outs at months 3 and 6 were excluded

M0 month 0, M6 month 6

^aValues are presented as means ± standard deviations. All analysis was conducted on the log-transformed values. General linear models were used to assess the impact of group on month 6 with M0 intake as a covariate and controlling for country where necessary