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. 2016 Sep 7;6(9):160153. doi: 10.1098/rsob.160153

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© 2016 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 2. — Function of hADA3 as a co-activator. hADA3 is part of the BTM and acts as a transcriptional co-activator to conduit the UAS to the BTM for the transcriptional activation of p53, ER, RAR, RXR, etc., in order to regulate various cellular functions that are crucial for normal cellular growth.