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Involvement of HPV16E6 oncoprotein in vitiation of hADA3 mediated functions. HPV16E6 oncoprotein, through its hijacking of hADA3, agitates the normal functions of several transcription modulators such as p300 and PCAF, causing deregulation of numerous TF, thus affecting a multitude of imperative physiological process culminating in tumorigenesis.
