Table 3.
Quality of Life measures
| Variable | Treatment Group | ||
|---|---|---|---|
| LLLT (N = 15) | Lorcaserin (N = 14) | Combination (N = 13a) | |
| LASA ± SD | |||
| Baseline | 8.0 ± 0.9 | 7.7 ± 1.8 | 7.4 ± 1.1 |
| Week 12 | 8.6 ± 0.9 | 8.6 ± 0.8 | 8.2 ± 1.3 |
| Delta | +0.6 ± 0.9b | +0.9 ± 1.9 | +0.8 ± 1.2b |
| CES-D ± SD | |||
| Baseline | 2.0 ± 3.6 | 4.1 ± 6.6 | 2.8 ± 3.3 |
| Week 12 | 3.3 ± 4.4 | 3.7 ± 4.3 | 3.4 ± 2.8 |
| Delta | +1.3 ± 2.5 | −0.4 ± 4.8 | +0.6 ± 2.8 |
| BAS ± SD | |||
| Baseline | 3.7 ± 0.6 | 3.7 ± 0.5 | 3.7 ± 0.7 |
| Week 12 | 3.6 ± 0.5 | 3.9 ± 0.7 | 3.8 ± 0.8 |
| Delta | −0.1 ± 0.6 | +0.3 ± 0.4b | +0.1 ± 0.7 |
| BASS ± SD | |||
| Baseline | 3.0 ± 0.4 | 3.0 ± 0.5 | 3.0 ± 0.4 |
| Week 12 | 3.1 ± 0.3 | 3.3 ± 0.5 | 3.0 ± 0.8 |
| Delta | +0.1 ± 0.4 | +0.3 ± 0.4b | 0.0 ± 0.6 |
| IWQOL - TOTAL ± SD | |||
| Baseline | 54.1 ± 12.1 | 50.9 ± 15.3 | 62.8 ± 22.4 |
| Week 12 | 47.9 ± 7.4 | 47.6 ± 15.6 | 54.9 ± 21.9 |
| Delta | −6.1 ± 10.4 | −3.3 ± 8.7 | −8.0 ± 7.9c |
BAS Body Appreciation Scale, BASS Body Area Satisfaction Scale, CESD-R Center for Epidemiologic Studies Depression Scale Revised, IWQOL-Lite Impact of Weight on Quality of Life - Lite, LASA Linear Analogue Self-Assessment, SD Standard Deviation
aOf the 15 subjects assigned to the combination group, 2 discontinued prior to week 12 and are not included in the analysis
b P < 0.05 for paired t-test comparing week 12 versus baseline
c P < 0.01 for paired t-test comparing week 12 versus baseline