Table 4.
Variable | LLLT (N = 15) | Lorcaserin (N = 14) | Combination (N = 13a) |
---|---|---|---|
RBC | |||
Baseline | 4.59 ± 0.32 | 4.75 ± 0.43 | 4.80 ± 0.41 |
Week 12 | 4.61 ± 0.29 | 4.70 ± 0.42 | 4.65 ± 0.34 |
Delta | +0.01 ± 0.20 | −0.06 ± 0.17 | −0.15 ± 0.26 |
Hemoglobin | |||
Baseline | 13.77 ± 0.92 | 14.34 ± 1.26 | 14.00 ± 1.26 |
Week 12 | 13.83 ± 0.81 | 14.08 ± 1.28 | 13.55 ± 1.15 |
Delta | +0.07 ± 0.57 | −0.26 ± 0.61 | −0.45 ± 0.86 |
Hematocrit | |||
Baseline | 41.35 ± 2.07 | 42.81 ± 3.00 | 42.17 ± 2.82 |
Week 12 | 41.53 ± 2.13 | 42.03 ± 2.92 | 40.78 ± 2.67 |
Delta | +0.17 ± 1.82 | −0.77 ± 1.93 | −1.39 ± 2.37 |
MCV | |||
Baseline | 90.19 ± 4.38 | 90.21 ± 3.18 | 88.09 ± 4.07 |
Week 12 | 90.29 ± 3.69 | 89.66 ± 3.76 | 87.86 ± 4.00 |
Delta | +0.10 ± 2.05 | −0.56 ± 2.08 | −0.23 ± 1.86 |
RDW | |||
Baseline | 13.23 ± 0.74 | 13.11 ± 0.50 | 13.41 ± 0.61 |
Week 12 | 13.19 ± 0.58 | 12.96 ± 0.49 | 13.22 ± 0.69 |
Delta | −0.04 ± 0.40 | −0.14 ± 0.37 | −0.19 ± 0.48 |
WBC | |||
Baseline | 6.83 ± 1.71 | 7.20 ± 1.45 | 6.98 ± 1.28 |
Week 12 | 5.99 ± 1.41 | 6.81 ± 2.11 | 6.32 ± 1.57 |
Delta | −0.83 ± 1.26* | −0.39 ± 1.08 | −0.66 ± 1.11 |
Neutrophils | |||
Baseline | 4.03 ± 1.58 | 4.15 ± 1.12 | 4.29 ± 1.08 |
Week 12 | 3.30 ± 1.10 | 3.99 ± 1.72 | 3.78 ± 1.20 |
Delta | −0.74 ± 1.17* | −0.16 ± 0.99 | −0.51 ± 0.77* |
Lymphocytes | |||
Baseline | 2.04 ± 0.41 | 2.22 ± 0.55 | 2.00 ± 0.39 |
Week 12 | 1.93 ± 0.38 | 2.03 ± 0.41 | 1.84 ± 0.53 |
Delta | −0.11 ± 0.25 | −0.19 ± 0.43 | −0.16 ± 0.39 |
Monocytes | |||
Baseline | 0.51 ± 0.13 | 0.60 ± 0.19 | 0.49 ± 0.13 |
Week 12 | 0.47 ± 0.13 | 0.58 ± 0.22 | 0.47 ± 0.10 |
Delta | −0.05 ± 0.12 | −0.02 ± 0.12 | −0.03 ± 0.06 |
Eosinophils | |||
Baseline | 0.22 ± 0.12 | 0.18 ± 0.11 | 0.16 ± 0.05 |
Week 12 | 0.26 ± 0.18 | 0.17 ± 0.11 | 0.19 ± 0.15 |
Delta | +0.04 ± 0.11 | −0.01 ± 0.06 | +0.03 ± 0.15 |
Basophils | |||
Baseline | 0.03 ± 0.02 | 0.04 ± 0.03 | 0.03 ± 0.02 |
Week 12 | 0.04 ± 0.02 | 0.04 ± 0.03 | 0.03 ± 0.01 |
Delta | +0.01 ± 0.02 | −0.00 ± 0.02 | +0.00 ± 0.01 |
Platelets | |||
Baseline | 251.4 ± 56.6 | 287.0 ± 69.3 | 292.9 ± 60.3 |
Week 12 | 253.4 ± 51.2 | 277.1 ± 70.9 | 287.4 ± 47.7 |
Delta | +2.0 ± 20.8 | −9.9 ± 27.3 | −5.5 ± 26.0 |
*p < 0.05, for paired t-test comparing week 12 versus baseline
aOf the 15 subjects assigned to the combination group, 2 discontinued prior to week 12 and are not included in the analysis