Table 5.

Lab values

Variable	LLLT (N = 15)	Lorcaserin (N = 14)	Combination (N = 13a)
Hgb_a1c
Baseline	5.59 ± 0.92	5.31 ± 0.51	5.36 ± 0.23
Week 12	5.71 ± 1.12	5.29 ± 0.43	5.33 ± 0.30
Delta	+0.12 ± 0.29	−0.02 ± 0.14	−0.03 ± 0.13
CRP
Baseline	4.72 ± 3.22	4.71 ± 3.62	4.60 ± 2.18
Week 12	4.81 ± 2.79	4.04 ± 2.55	5.97 ± 5.69
Delta	+0.09 ± 1.86	−0.68 ± 1.40	+1.37 ± 5.61
LDL
Baseline	111.3 ± 28.7	95.1 ± 19.0	117.5 ± 31.0
Week 12	115.1 ± 29.4	94.9 ± 20.8	107.0 ± 28.8
Delta	+3.8 ± 22.2	−0.3 ± 17.8	−10.5 ± 22.2
Non-HDL Cholesterol
Baseline	137.5 ± 33.0	128.4 ± 27.2	141.8 ± 34.7
Week 12	139.5 ± 37.3	121.6 ± 30.7	128.7 ± 33.7
Delta	+2.0 ± 24.6	−6.8 ± 18.8	−13.1 ± 24.2
HDL
Baseline	62.3 ± 14.5	53.6 ± 14.5	60.3 ± 16.7
Week 12	61.5 ± 17.5	51.3 ± 12.7	56.5 ± 15.7
Delta	−0.8 ± 7.5	−2.3 ± 7.1	−3.8 ± 7.7
Triglycerides
Baseline	130.7 ± 48.7	166.1 ± 98.5	119.8 ± 51.5
Week 12	121.9 ± 62.3	134.1 ± 85.3	108.7 ± 50.1
Delta	−8.9 ± 39.7	−32.1 ± 39.0**	−11.2 ± 56.2
Total Cholesterol
Baseline	199.8 ± 29.0	182.0 ± 26.7	202.1 ± 27.3
Week 12	201.0 ± 35.7	172.9 ± 30.8	185.2 ± 33.0
Delta	+1.2 ± 30.1	−9.1 ± 23.5	−16.8 ± 24.2*
Fasting Glucose
Baseline	89.7 ± 11.7	90.6 ± 14.6	88.6 ± 13.6
Week 12	92.5 ± 20.1	60.2 ± 17.8	87.7 ± 8.7
Delta	+2.8 ± 10.9	−0.4 ± 7.0	−0.9 ± 8.1
Leptin
Baseline	38.1 ± 15.7	35.7 ± 21.2	37.2 ± 26.0
Week 12	34.0 ± 12.4	34.1 ± 23.6	30.8 ± 21.4
Delta	−4.1 ± 11.6	−1.6 ± 11.3	−6.4 ± 12.1
Adiponectin
Baseline	9,719 ± 5,534	7,955 ± 3,463	12,412 ± 8,393
Week 12	8,987 ± 4,050	7,156 ± 2,231	12,254 ± 7,273
Delta	−732 ± 3,970	−799 ± 2,237	−158 ± 2,787

^* p < 0.05, ^** p < 0.01for paired t-test comparing week 12 versus baseline

^aOf the 15 subjects assigned to the combination group, 2 discontinued prior to week 12 and are not included in the analysis