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. 2016 Sep 29;14:284. doi: 10.1186/s12967-016-1030-6

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Representative images of non-PAD and PAD gastrocnemius muscle sections stained for mitochondrial activity and mitochondrial electron transport proteins. Top row shows succinate dehydrogenase (SDH) activity (dark fibers are type I, intermediate fibers are type IIa, and light fibers are type IIa/x), second row shows mitochondrial complex I, subunit 20 (orange), third row shows mitochondrial complex IV, subunit I (COX-1; green) staining and bottom row shows complex I and COX-1 merged. Arrows within the same column point to same fibers. Scale bar = 50 µm