Table 1.
Characteristics of control and DOCA animals
| Controls (n = 7) | DOCA (n = 5) | Controls vs. DOCA | ||||||
|---|---|---|---|---|---|---|---|---|
| Parameter | Rest | Stress | p | Rest | Stress | p | prest | pstress |
| weight (kg) | 58 ± 9 | 65 ± 2 | 0.090 | |||||
| BSA (m2) | 1.05 ± 0.10 | 1.14 ± 0.03 | 0.085 | |||||
| Htc (%) | 28 ± 2 | 28 ± 2 | 0.796 | |||||
| DB (μg · kg−1 · min−1) | 2.7 ± 0.7 | 3.8 ± 1.0 | 0.045 | |||||
| HR (min−1) | 89 ± 5 | 114 ± 3 | < 0.001 | 86 ± 8 | 110 ± 13 | 0.014 | 0.424 | 0.488 |
| mBP (mmHg) | 87 ± 7 | 95 ± 13 | 0.061 | 106 ± 8 | 101 ± 12 | 0.538 | 0.001 | 0.400 |
| sBP (mmHg) | 103 ± 8 | 116 ± 9 | 0.004 | 125 ± 6 | 120 ± 11 | 0.536 | < 0.001 | 0.493 |
| dBP (mmHg) | 75 ± 9 | 82 ± 16 | 0.077 | 96 ± 10 | 86 ± 12 | 0.122 | 0.003 | 0.614 |
| RPP (102 mmHg · min−1) | 92 ± 8 | 132 ± 11 | < 0.001 | 108 ± 14 | 132 ± 17 | 0.026 | 0.034 | 0.990 |
BSA body surface area, Htc hematocrit, DB dobutamine infusion rate, HR heart rate, mBP mean blood pressure, sBP systolic blood pressure, dBP diastolic blood pressure, RPP (= sBP × HR) rate-pressure product
p is related to the rest-stress comparison within each group. prest and pstress relate to group comparisons at rest and stress, respectively