Table 2.
Parameters of cardiac and myocardial geometry and function
| Controls (n = 7) | DOCA (n = 5) | Controls vs. DOCA | ||||||
|---|---|---|---|---|---|---|---|---|
| Parameter | Rest | Stress | p | Rest | Stress | p | prest | pstress |
| LVMM (g · m−2) | 84 ± 7 | 111 ± 9 | <0.001 | |||||
| WTED (mm · m−2) | 6.3 ± 1.2 | 6.2 ± 1.4 | 0.934 | 8.3 ± 0.8 | 9.3 ± 1.6 | 0.224 | 0.007 | 0.006 |
| WTES (mm · m−2) | 9.6 ± 1.6 | 11.8 ± 2.2 | 0.009 | 13.0 ± 1.4 | 15.5 ± 1.9 | 0.012 | 0.003 | 0.012 |
| WTH (mm · m−2) | 3.3 ± 0.8 | 5.6 ± 1.7 | 0.019 | 4.8 ± 0.9 | 6.2 ± 1.1 | 0.074 | 0.020 | 0.489 |
| MAPSE (mm) | 11.1 ± 3.6 | 15.0 ± 3.7 | 0.078 | 6.9 ± 1.2 | 13.5 ± 4.9 | 0.040 | 0.037 | 0.586 |
| EF (%) | 52 ± 3 | 69 ± 7 | 0.001 | 53 ± 5 | 70 ± 2 | < 0.001 | 0.840 | 0.749 |
| EDV (ml · m−2) | 124 ± 15 | 117 ± 12 | 0.293 | 125 ± 18 | 102 ± 26 | 0.008 | 0.862 | 0.203 |
| ESV (ml · m−2) | 59 ± 9 | 36 ± 10 | 0.005 | 59 ± 10 | 30 ± 9 | < 0.001 | 0.983 | 0.360 |
| SV (ml · m−2) | 65 ± 8 | 81 ± 9 | 0.003 | 66 ± 11 | 71 ± 17 | 0.352 | 0.781 | 0.244 |
| CI (l min−1 · m−2) | 5.8 ± 0.9 | 9.4 ± 1.1 | < 0.001 | 5.8 ± 1.0 | 7.8 ± 1.2 | 0.002 | 0.890 | 0.041 |
| PER (ml · s−1 · m−2) | −380 ± 54 | −711 ± 219 | 0.005 | −419 ± 95 | −639 ± 114 | 0.002 | 0.389 | 0.523 |
| PFRE (ml · s−1 · m−2) | 307 ± 41 | 470 ± 75 | 0.002 | 332 ± 69 | 471 ± 49 | 0.007 | 0.449 | 0.979 |
| PFRA (ml · s−1 · m−2) | 302 ± 73 | 345 ± 99 | 0.223 | 334 ± 133 | 277 ± 118 | 0.192 | 0.599 | 0.304 |
| LAVmax (ml · m−2) | 34 ± 4 | 32 ± 8 | 0.444 | 48 ± 17 | 34 ± 14 | 0.012 | 0.042 | 0.798 |
| LAVmin (ml · m−2) | 14 ± 3 | 14 ± 4 | 0.655 | 25 ± 9 | 21 ± 8 | 0.222 | 0.012 | 0.054 |
| LATEF (%) | 58 ± 4 | 58 ± 11 | 0.990 | 48 ± 14 | 36 ± 10 | 0.265 | 0.104 | 0.006 |
LVMM left ventricular muscle mass, WT ED end-diastolic wall thickness, WT ES end-systolic wall thickness, WTH wall thickening, MAPSE mitral annular plane systolic excursion, EF left ventricular ejection fraction, EDV left ventricular end-diastolic volume, ESV left ventricular end-systolic volume, SV left ventricular stroke volume, CI left ventricular cardiac index, PER peak ejection rate, PFR E early diastolic peak filling rate, PFR A late diastolic peak filling rate, LAV max left atrial maximum volume, LAV min left atrial minimal volume, LATEF left atrial total ejection fraction
p is related to the rest-stress comparison within each group. prest and pstress relate to group comparisons at rest and stress, respectively