Table 3.
Correlation between MMP and TIMP Serum Levels and Subscale HAMD Scores in MD Groups
| Core symptom | Sleep | Activity | Psychic Anxiety | Somatic Anxiety | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Rho | P | Rho | P | Rho | P | Rho | P | Rho | P | |
| MMP-2 | -0.339 | .028* | -0.191 | .225 | -0.322 | .038* | -0.180 | .253 | -0.350 | .023* |
| TIMP-2 | -0.085 | .593 | 0.072 | .650 | -0.124 | .434 | -0.025 | .875 | -0.022 | .891 |
| MMP-9 | 0.399 | .009** | 0.169 | .285 | 0.457 | .020* | 0.316 | .041* | 0.363 | .018* |
| TIMP-1 | 0.049 | .759 | 0.078 | .625 | 0.047 | .766 | -0.018 | .911 | 0.204 | .195 |
Abbreviations: HAMD, Hamilton Rating Score for Depression; MD, mood disorder; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of MMP.
*P < .05, **P < .01.