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Fluoxetine inhibited NLRP3 inflammasome activation in bone marrow-derived macrophages (BMDMs) of chronic mild stress (CMS) mice. (A) Serum interleukin (IL)-1β levels by ELISA (n=18/groups). Representative immunoblots (B) and quantitative analysis of NLRP3 (C), caspase-1 (D), and IL-1β (E) in BMDMs of CMS mice (n=4/groups). Data are represented as means ± SEM. ** P<.01, *** P<.001 vs CMS.
