Table 4. Actual Plasma Concentrations of Paliperidone ER:Descriptive Statistics.
ACTUAL PLASMA CONCENTRATION (ng/mL) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
n | MEAN | (SD) | %CV | MEDIAN | |||||||
Paliperidone ER 1.5 mg | |||||||||||
Day −1 | Predose | 64 | BQL | (−) | - | BQL | |||||
Day 8 | Predose | 56 | 5.08 | 3.65 | 71.8 | 4.48 | |||||
1-3 hr postdose | 54 | 4.95 | 3.51 | 71 | 4.53 | ||||||
6 hr postdose | 54 | 4.87 | 3.53 | 72.5 | 4.47 | ||||||
Paliperidone ER 6 mg | |||||||||||
Day −1 | Predose | 68 | BQL | (−) | - | BQL | |||||
Day 8 | Predose | 61 | 27.4 | 19.3 | 70.3 | 21.6 | |||||
1-3 hr postdose | 62 | 26.3 | 19.5 | 74.1 | 20 | ||||||
6 hr postdose | 62 | 24.3 | 16.6 | 68.4 | 19 |
BQL−below quantifiable limit.