Table 1.
The 10 most differentially methylated probes after Bonferroni's correction (p < 10–7; β > 0.2) in the different areas analyzed between schizophrenic and healthy samples.
| Feature ID | Chr | Gene region | Schizophrenic | Healthy | Difference (mean) | |||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||||
| DLPFC | ||||||||
| Undefined | 4 | Intergenic | 0.65 | 0.13 | 0.06 | 0.04 | 0.59 | |
| NUBP1 | 16 | Body | 0.89 | 0.03 | 0.46 | 0.00 | 0.43 | |
| STK32B | 4 | Body | 0.82 | 0.02 | 0.41 | 0.04 | 0.40 | |
| AIG1 | 6 | Body | 0.81 | 0.03 | 0.42 | 0.02 | 0.38 | |
| PRKCE | 2 | Body | 0.81 | 0.02 | 0.43 | 0.00 | 0.38 | |
| FAM69C | 18 | 3′UTR | 0.49 | 0.20 | 0.88 | 0.00 | −0.38 | |
| RASA3 | 13 | Body | 0.50 | 0.20 | 0.90 | 0.02 | −0.40 | |
| RASA3 | 13 | Body | 0.46 | 0.20 | 0.87 | 0.02 | −0.41 | |
| Undefined | 17 | Intergenic | 0.50 | 0.17 | 0.93 | 0.04 | −0.42 | |
| ATP11A | 13 | 3′UTR | 0.33 | 0.14 | 0.90 | 0.01 | −0.56 | |
| HIPPOCAMPUS | ||||||||
| Non-defined | 14 | Intergenic | 0.70 | 0.16 | 0.15 | 0.18 | 0.54 | |
| HLA-DQA1 | 6 | Body | 0.60 | 0.13 | 0.10 | 0.07 | 0.49 | |
| Non-defined | 16 | Intergenic | 0.78 | 0.02 | 0.30 | 0.03 | 0.48 | |
| HCN2 | 19 | Body | 0.59 | 0.14 | 0.13 | 0.12 | 0.46 | |
| Non-defined | 6 | Intergenic | 0.75 | 0.15 | 0.29 | 0.04 | 0.46 | |
| Non-defined | 16 | Intergenic | 0.87 | 0.13 | 0.42 | 0.10 | 0.44 | |
| AJAP1 | 1 | Body | 0.16 | 0.19 | 0.55 | 0.20 | −0.38 | |
| HLA-B | 6 | 3′UTR | 0.14 | 0.05 | 0.57 | 0.20 | −0.43 | |
| Non-defined | 2 | Intergenic | 0.38 | 0.01 | 0.87 | 0.00 | −0.49 | |
| HLA-DRB5 | 6 | Body | 0.36 | 0.19 | 0.88 | 0.05 | −0.51 | |
| ACC | ||||||||
| C4orf50 | 4 | 3′UTR | 0.75 | 0.15 | 0.28 | 0.20 | 0.47 | |
| Undefined | 14 | Intergenic | 0.64 | 0.20 | 0.16 | 0.19 | 0.47 | |
| GALNT1 | 18 | 5′UTR | 0.84 | 0.03 | 0.45 | 0.06 | 0.39 | |
| VSX2 | 14 | TSS1500 | 0.54 | 0.18 | 0.16 | 0.20 | 0.38 | |
| SAPS2 | 22 | Body | 0.80 | 0.09 | 0.44 | 0.08 | 0.35 | |
| KCNK7 | 11 | 1st Exon | 0.42 | 0.20 | 0.77 | 0.04 | −0.35 | |
| Undefined | 14 | Intergenic | 0.35 | 0.18 | 0.71 | 0.04 | −0.35 | |
| CSMD2 | 1 | Body | 0.25 | 0.14 | 0.62 | 0.20 | −0.37 | |
| FRK | 6 | 3′UTR | 0.39 | 0.15 | 0.83 | 0.03 | −0.43 | |
| TUBAL3 | 10 | TSS200 | 0.11 | 0.18 | 0.69 | 0.18 | −0.58 | |
Chr, Chromosome. TSS, Transcription start site.